Indications: Management of HIV infection (AIDS) in combination with other antiretrovirals.
Abacavir will slow down the progression of HIV infection and decreases the occurrence of its sequelae, it increases CD4 cell counts and decreases viral load.
The absorption of this drug is rapidly and extensively (83%) absorbed. It is distributed into extra-vascular space and readily distributes into erythrocytes. Mostly metabolized by the liver; 1.2% excreted unchanged in urine. It will take 1.5 hour of its half-life.
Contraindicated in: Hypersensitivity, Lactation
Adverse reaction and side effects:
For CNS you will experience headache, insomia
For GI: hepatotoxicity, diarrhea, nausea, vomiting, anorexia
For Derma: rashes
Route and Dosage:
PO (Adults): 300 mg twice dailly
PO (Children 3 mo- 16 yr): 8 mg/kg twice daily (not to exceed 300 mg twice daily)
Tablets: 300 mg
Oral solution (strawberry/banana flavor): 20 mg/ml om 240-ml bottles
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